Figure 7.

Schematic diagram of COL10A1-related IDD molecular mechanism. The red line represents positive regulation, the green line represents negative regulation, and the arrow represents the direction of regulation. The solid line represents the verified regulatory relationship, and the dashed line represents the regulatory hypothesis proposed in this study. COL10A1 may be negatively regulated by miR-5100, while lncRNA LINC00475, SOX2-OT, NEAT1, SNHG12, GAS5, AGAP2-AS1, and TARID may act as ceRNA for competitively binding miR-5100 and thus correcting the negative regulation of miR-5100, inducing IDD.