Table 1.
The basic information of the datasets obtained from GEO database.
| Dataset | Type of RNAs tested | Samples | Experimental group | Control group | Platform |
|---|---|---|---|---|---|
| GSE34095 | mRNA | 6 | Degenerative nucleus pulposus from IDD patients | Nucleus pulposus from scoliosis patients | GPL96 [HG-U133A] Affymetrix Human Genome U133A Array |
| GSE70362 | mRNA | 24 | Degenerative nucleus pulposus (Thompson grade III–V) | Degenerative nucleus pulposus (Thompson grade I–II) | GPL17810 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array [CDF: Brainarray HGU133Plus2_Hs_ENTREZG_v16] |
| GSE112216 | mRNA, lncRNA | 6 | Degenerative nucleus pulposus derived cells cocultured with adipose derived stem cell | Degenerative nucleus pulposus derived cells | GPL16686 [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
| GSE114169 | mRNA | 8 | Degenerative nucleus pulposus cultured 1 week with Neurotropin | Degenerative nucleus pulposus cultured 1 week with none | GPL17077 Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version) |
| GSE118927 | mRNA, lncRNA | 6 | Degenerative nucleus pulposus derived cells cocultured with adipose derived stem cell | Degenerative nucleus pulposus derived cells | GPL16686 [HuGene-2_0-st] Affymetrix Human Gene 2.0 ST Array [transcript (gene) version] |
| GSE124272 | mRNA | 16 | Peripheral blood from IDD patients | Peripheral blood from healthy people | GPL21185 Agilent-072363 SurePrint G3 Human GE v3 8x60K Microarray 039494 [Probe Name version] |
| GSE19943 | miRNA | 6 | Degenerative nucleus pulposus from IDD patients | Nucleus pulposus from scoliosis patients | GPL9946 Exiqon human miRCURY LNA™ microRNA Array V11.0 |
| GSE63492 | miRNA | 10 | Degenerative nucleus pulposus | Nondegenerative nucleus pulposus | GPL19449 Exiqon miRCURY LNA microRNA Array; 7th generation REV-hsa; mmu & rno (miRBase v18.0) |
| GSE116726 | miRNA | 6 | Degenerative nucleus pulposus from IDD patients | Nucleus pulposus from traumatic lumbar fracture | GPL20712 Agilent-070156 Human miRNA [miRNA version] |
| GSE56081 | lncRNA | 10 | Degenerative nucleus pulposus | Nondegenerative nucleus pulposus | GPL15314 Arraystar Human LncRNA microarray V2.0 (Agilent_033010 Probe Name version) |
| GSE67566 | circRNA | 10 | Degenerative nucleus pulposus | Nondegenerative nucleus pulposus | GPL19978 Agilent-069978 Arraystar Human CircRNA microarray V1 |