Table 1.
Characteristics | N (%) | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | ||
Gender | |||||
Female | 26 (12.56) | Reference | — | Reference | — |
Male | 181 (87.44) | 0.64 (0.41–1.01) | 0.06 | 0.55 (0.34–0.90) | 0.02 |
| |||||
Age | |||||
<60 | 133 (64.25) | Reference | — | Reference | — |
≥60 | 74 (35.75) | 1.46 (1.05–2.02) | 0.024 | 1.04 (0.73–1.49) | 0.81 |
| |||||
TCM syndrome | |||||
Deficiency | 36 (17.39) | Reference | — | Reference | — |
Excess | 98 (47.34) | 0.39 (0.25–0.60) | <0.001 | 0.58 (0.36–0.95) | 0.03 |
Intermingled | 73 (35.27) | 0.71 (0.46–1.10) | 0.13 | 1.05 (0.64–1.74) | 0.84 |
| |||||
Tumor size | |||||
<5 | 115 (55.56) | Reference | — | Reference | — |
≥5 | 92 (44.44) | 4.12 (2.94–5.77) | <0.001 | 3.99 (2.74–5.81) | <0.001 |
| |||||
Tumor number | |||||
Single | 113 (54.59) | Reference | — | Reference | — |
≥2 | 94 (45.41) | 3.02 (2.17–4.21) | <0.001 | 2.13 (1.48–3.06) | <0.001 |
| |||||
Surgery | |||||
Yes | 33 (15.94) | Reference | — | Reference | — |
No | 174 (84.06) | 5.16 (2.63–10.15) | <0.001 | 4.25 (2.03–8.88) | <0.001 |
| |||||
Child–Pugh | |||||
A | 136 (65.70) | Reference | — | Reference | — |
B | 52 (25.12) | 2.44 (1.69–3.51) | <0.001 | 2.01 (0.68–1.69) | <0.01 |
C | 19 (9.18) | 4.61 (2.76–7.72) | <0.001 | 2.42 (0.48–2.08) | 0.02 |
| |||||
ALBI | |||||
≤−2.6 | 81 (39.13) | Reference | — | Reference | — |
>−2.6, ≤−1.39 | 103 (49.76) | 2.16 (1.50–3.11) | <0.001 | 1.08 (0.68–1.69) | 0.75 |
>−1.39 | 23 (11.11) | 4.42 (2.61–7.48) | <0.001 | 1.00 (0.48–2.08) | 0.99 |
| |||||
HBV-DNA | |||||
<500 | 76 (36.71) | Reference | — | Reference | — |
≥500 | 131 (63.29) | 2.01 (1.41–2.87) | <0.001 | 1.30 (0.89–1.89) | 0.17 |