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. 2021 Jun 29;2021:9991533. doi: 10.1155/2021/9991533

Table 1.

Results of univariate and multivariate analyses.

Characteristics N (%) Univariate analysis Multivariate analysis
HR (95% CI) P HR (95% CI) P
Gender
 Female 26 (12.56) Reference Reference
 Male 181 (87.44) 0.64 (0.41–1.01) 0.06 0.55 (0.34–0.90) 0.02

Age
 <60 133 (64.25) Reference Reference
 ≥60 74 (35.75) 1.46 (1.05–2.02) 0.024 1.04 (0.73–1.49) 0.81

TCM syndrome
 Deficiency 36 (17.39) Reference Reference
 Excess 98 (47.34) 0.39 (0.25–0.60) <0.001 0.58 (0.36–0.95) 0.03
 Intermingled 73 (35.27) 0.71 (0.46–1.10) 0.13 1.05 (0.64–1.74) 0.84

Tumor size
 <5 115 (55.56) Reference Reference
 ≥5 92 (44.44) 4.12 (2.94–5.77) <0.001 3.99 (2.74–5.81) <0.001

Tumor number
 Single 113 (54.59) Reference Reference
 ≥2 94 (45.41) 3.02 (2.17–4.21) <0.001 2.13 (1.48–3.06) <0.001

Surgery
 Yes 33 (15.94) Reference Reference
 No 174 (84.06) 5.16 (2.63–10.15) <0.001 4.25 (2.03–8.88) <0.001

Child–Pugh
 A 136 (65.70) Reference Reference
 B 52 (25.12) 2.44 (1.69–3.51) <0.001 2.01 (0.68–1.69) <0.01
 C 19 (9.18) 4.61 (2.76–7.72) <0.001 2.42 (0.48–2.08) 0.02

ALBI
 ≤−2.6 81 (39.13) Reference Reference
 >−2.6, ≤−1.39 103 (49.76) 2.16 (1.50–3.11) <0.001 1.08 (0.68–1.69) 0.75
 >−1.39 23 (11.11) 4.42 (2.61–7.48) <0.001 1.00 (0.48–2.08) 0.99

HBV-DNA
 <500 76 (36.71) Reference Reference
 ≥500 131 (63.29) 2.01 (1.41–2.87) <0.001 1.30 (0.89–1.89) 0.17