Table 3. Stroke burden after adjustments.

Variables			LAAO (n=30)	NOAC (n=86)	p value
Before adjustment
	mRS before the event		0.3±0.2	0.6±0.1	0.22
	mRS at discharge		1.8±0.3	2.7±0.2	0.03
	mRS at 3 months		1.1±0.4	2.6±0.2	<0.01
	mRS at 12 months		1.0±0.4	2.5±0.2	<0.01
After adjustment
	Model 1*
		mRS at discharge	1.8±0.3	2.7±0.2	0.03
		mRS at 3 months	1.1±0.4	2.6±0.2	<0.01
		mRS at 12 months	1.0±0.4	2.5±0.2	<0.01
	Model 2*
		mRS at discharge	1.8±0.3	2.7±0.2	0.03
		mRS at 3 months	1.1±0.4	2.6±0.2	<0.01
		mRS at 12 months	1.1±0.4	2.5±0.2	<0.01
	Model 3*
		mRS at discharge	1.9±0.3	2.6±0.2	0.07
		mRS at 3 months	1.2±0.4	2.5±0.2	<0.01
		mRS at 12 months	1.1±0.4	2.5±0.2	<0.01

Data are presented as the least square mean±standard error.

LAAO = left atrial appendage occlusion; mRS = modified Rankin Scale; NOAC = non-vitamin K antagonist oral anticoagulant.

^*Model 1: adjusted for CHA₂DS₂-VASc score. Model 2: similar to model 1, with the additional inclusion of HAS-BLED score. Model 3: similar to model 2, with the additional inclusion of age, gender, and cardiovascular risk factors (age, sex, hypertension, diabetes mellitus, congestive heart failure and previous stroke/transient ischemic attack).