Table 1.
Patient characteristics.
| Group A (HLA-mismatched) | fraction | Group B (HLA-Matched) | fraction | p-value | |
|---|---|---|---|---|---|
| Total | 39 | 27 | |||
| Gender | |||||
| m | 24 | 0.62 | 18 | 0.67 | n.s. |
| f | 15 | 0.38 | 8 | 0.33 | |
| Age at diagnosis | |||||
| ≤14 | 27 | 0.69 | 13 | 0.48 | n.s. |
| >14 | 12 | 0.31 | 14 | 0.52 | |
| Number of allele mismatch (Group A) | |||||
| Haploidentical | 28 | n.a. | n.a. | ||
| 2/10 | 6 | n.a. | n.a. | ||
| 3/10 | 2 | n.a. | n.a. | ||
| 4/10 | 3 | n.a. | n.a. | ||
| Eligibility for allo-SCT | |||||
| Multifocal/progressive primary disease | 12 | 31% | 17 | 63% | n.s. |
| Relapse | 27 | 69% | 10 | 37% | |
| First relapse | 13 | 33% | 6 | 22% | |
| Second relapse | 9 | 23% | 2 | 7% | |
| Third relapse | 5 | 13% | 0 | 0% | |
| Unknown | 0 | 0% | 2 | 7% | |
| Remission at allo-SCT | |||||
| CR | 14 | 0.36 | 8 | 0.3 | n.s. |
| Other | 25 | 0.64 | 19 | 0.7 | |
| Risk stratum | |||||
| R1 + R2loc | 10 | 0.26 | 4 | 0.15 | n.s. |
| R2pulm | 5 | 0.12 | 4 | 0.15 | |
| R3 (extrapulm met) | 24 | 0.62 | 19 | 0.7 | |
m male, f female, CR complete remission, R1 + R2loc localized disease, R2pulm localized disease with pulmonary metastases, R3(extrapulm met) ≥2 bone metastases at diagnosis, allo-SCT allogeneic stem cell transplantation, n.s. not significant.