Table 2.
Minimum inhibitory concentration (MIC) of fractions (see Supplementary Figure S1) obtained from acetonitrile: water (3:2) extract of Evernia prunastri
| Fraction | Yield (mg) | MIC, µg/ml | |||
|---|---|---|---|---|---|
| Staphylococcus aureus | Pseudomonas aeruginosa | Escherichia coli | Candida albicans | ||
| I | 5 | > 500 | > 500 | 250 | 500 |
| II | 3.4 | > 500 | > 500 | > 500 | > 500 |
| III | 12.4 | 62.5 | > 500 | > 500 | > 500 |
| IV | 10.7 | > 500 | > 500 | 500 | > 500 |
| V | 10.6 | 1.95 | 31.25 | 31.25 | 62.5 |
| VI | 31.8 | 0.98 | 31.25 | 125 | 62.5 |
| VII | 31.1 | 1.95 | > 500 | > 500 | 31.25 |
| VIII | 44.9 | 0.49 | > 500 | > 500 | 62.5 |
| IX | 12.6 | 3.91 | > 500 | > 500 | 125 |
| X | 13.0* | > 500 | 125 | 500 | > 500 |
| XI | 500 | 125 | 500 | > 500 | |
| XII | 500 | 500 | > 500 | > 500 | |
| XIII | 125 | 500 | > 500 | > 500 | |
| XIV | 11.8 | 15.63 | > 500 | > 500 | 500 |
| XV | 224.6 | 125 | 125 | 500 | 500 |
*Fraction after #IX (with mass 13 mg) was further separated using RP-HPLC into 4 more fractions
Numbers in bold indicate susceptibility or intermediate antibacterial activity