Table 1.
Baseline sociodemographic and clinical characteristics of study participants included in the analysis.
| Cohort of PLHIV | PLHIV with CD4 ≤200 cells/mm3 | |||
|---|---|---|---|---|
| Clinician-directed testing | Lab reflex testing | Clinic-based testing | ||
| (N=3,105) | (N=323) | (N=363) | (N=222) | |
| Baseline characteristics | n (%) | n (%) | n (%) | n (%) |
| Sociodemographics | ||||
| Age (years): mean (±SD) | 33.2 (9.3) | 35.1 (8.9) | 35.7 (9.8) | 36.0 (9.4) |
| Female gender | 1,331 (42.9) | 165 (51.1) | 198 (54.5) | 114 (51.4) |
| Completed high school or higher degree | 1,525 (49.1) | 112 (34.7) | 162 (44.6) | 136 (61.3) |
| Marital status | ||||
| Married | 193 (6.2) | 21 (6.5) | 22 (6.1) | 13 (5.8) |
| Single (never married) | 2,879 (92.7) | 298 (92.3) | 338 (93.1) | 203 (91.4) |
| Widowed/Divorced | 33 (1.1) | 4 (1.2) | 3 (0.8) | 6 (2.7) |
| Number of children (N=3,086)* | ||||
| No children | 585 (19.0) | 58 (17.9) | 68 (18.9) | 45 (20.5) |
| ≥1 children | 2,501 (81.0) | 264 (82.0) | 292 (81.1) | 174 (79.5) |
| Employed | 1,312 (42.3) | 149 (46.1) | 156 (43.0) | 97 (43.7) |
| Income level ZAR <2,000 Rand (~USD $150) (N=3,078)* | 2,226 (72.3) | 246 (77.1) | 262 (72.4) | 127 (57.5) |
| HIV and Medical History | ||||
| Previously received HIV testing | 2,390 (77.0) | 220 (68.1) | 228 (62.8) | 209 (94.1) |
| Previously tested HIV positive, among those tested (N=2,380)* | 791 (33.2) | 41 (18.9) | 77 (33.9) | 98 (46.7) |
| Partner HIV status (N=3,087)* | ||||
| HIV-positive | 847 (27.4) | 88 (27.4) | 91 (25.2) | 53 (24.8) |
| HIV-negative | 508 (16.5) | 40 (12.5) | 48 (13.3) | 18 (8.4) |
| Unknown | 1,732 (56.1) | 193 (60.1) | 222 (61.5) | 143 (66.8) |
| Ever tested Cryptococcus positive | 6 (0.2) | 2 (0.6) | 2 (0.6) | 0 (0.0) |
| Ever received Cryptococcus treatment, among those positive | 4 (0.1) | 1 (0.3) | 2 (0.6) | - |
| Clinical Symptoms and Signs | ||||
| Headache for >24 hours | 703 (22.6) | 113 (35.0) | 68 (18.7) | 33 (14.9) |
| Fever | 698 (22.5) | 122 (37.8) | 116 (32.0) | 45 (20.3) |
| Neck stiffness | 503 (16.2) | 71 (22.0) | 72 (19.8) | 42 (18.9) |
| Blurry or double vision | 325 (10.5) | 39 (12.1) | 52 (14.3) | 46 (20.7) |
| Confusion | 216 (7.0) | 20 (6.2) | 32 (8.8) | 18 (8.1) |
| Seizure with the prior 7 days | 26 (0.8) | 6 (1.9) | 3 (0.8) | 3 (1.4) |
| CD4 T-cell Count (cells/mm3) | ||||
| Baseline CD4 count using lab-based test (N=3,057): median (IQR) | 313 (173 – 486) | 108 (51 – 151) | 101 (45 – 147) | 121 (65 – 161) |
| Baseline CD4 count using POC test (N=720): median (IQR)** | 361 (214 – 563) | -- | -- | 147 (95 – 214) |
IQR: interquartile range, SD: standard deviation.
*
Does not sum to column total due to missing data.
**
Intervention period was clinic-based testing period only.