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. 2021 Jul 7;12:4197. doi: 10.1038/s41467-021-24489-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a The tSNE plot of the full 68 k PBMC dataset with rare cell types labeled in different colours. b Heatmap of the top differentially expressed genes between minor cluster R1 and the remaining CD14+ monocytes. c Expression distribution of 218 genes with absolute log₂ fold-change larger than 1 between the minor cluster R1 and the remaining CD14+ monocytes. d Heatmap of the top differentially expressed genes between minor cluster R2 and the remaining CD34+ cell population.