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. 2021 Jul 7;11:13984. doi: 10.1038/s41598-021-93549-2

Table 1.

General characteristics and clinical data of cases and controls, n (%) or medians (IQRs).

Variables Cases (n = 303) Controls (n = 303) χ2 or Z P-value*
Sex 0.000 1.00
Males 213 (70.30) 213 (70.30)
Females 90 (29.70) 90 (29.70)
Age 7.611 0.02
 < 40 90 (29.70) 80 (26.40)
40–60 196 (64.69) 187 (61.72)
 ≥ 60 17 (5.61) 36 (11.88)
Educational level 3.644 0.06
Junior middle school and less than 62 (20.46) 82 (27.06)
Senior high school and above 241 (79.54) 221 (72.94)
Occupational status 0.334 0.85
Mental labour 69 (22.77) 69 (22.77)
Physical labor 81 (26.73) 87 (28.71)
Other 153 (50.50) 147 (48.52)
Income (yuan/month) 0.489 0.78
 < 2000 1 (5.61) 16 (5.28)
2000–3000 93 (30.69) 101 (33.33)
 ≥ 3000 193 (63.70) 186 (61.39)
Marital status 0.868 0.35
Single 28 (9.24) 35 (11.55)
Married or other 275 (90.76) 268 (88.45)
Smoking status 0.638 0.42
Never smoker 208 (68.65) 217 (71.62)
Smoker 95 (31.35) 86 (28.38)
Teaing status 2.009 0.16
Yes 194 (64.03) 177 (58.42)
No 109 (35.97) 126 (41.58)
Exercise (times/week) 1.961 0.16
 < 3 118 (38.94) 135 (44.55)
 ≥ 3 185 (61.06) 168 (55.45)
History of diabetes 1.568 0.21
Yes 26 (8.58) 18 (5.94)
No 277 (91.42) 285 (94.06)
History of hypertension 17.128  < 0.001
Yes 103 (33.99) 58 (19.14)
No 200 (66.01) 245 (80.86)
History of hyperlipidemia 16.574  < 0.001
Yes 132 (43.56) 84 (27.72)
No 171 (56.44) 219 (72.28)
ALT (IU/L) 27.00 (21.00,40.00) 19.00 (14.00,26.00)  − 0.968  < 0.001
AST (IU/L) 23.00 (19.00,29.00) 20.00 (18.00,25.00)  − 5.014  < 0.001
GGT (IU/L) 30.00 (22.00,46.00) 22.00 (16.00,32.00)  − 7.662  < 0.001
TC (mmol/L) 5.13 (4.57,5.78) 4.91 (4.45,5.43)  − 2.643 0.01
TG (mmol/L) 1.76 (1.26,2.59) 1.12 (0.86,1.54)  − 10.416  < 0.001
HDL-C (mmol/L) 1.19 (1.03,1.37) 1.35 (1.20,1.48)  − 7.235  < 0.001
LDL-C (mmol/L) 3.12 (2.56,3.77) 3.01 (2.60,3.51)  − 1.201 0.23
CES1 (ng/ml) 13.25 (10.70,19.14) 13.13 (10.63,20.88)  − 0.235 0.81

ALT, alanine aminotransferase; AST, aspartate aminotransferase; GGT, gamma-glutamyltransferase; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; CES1, carboxylesterase 1.

*P-values were calculated by using the Chi-square test for categorical variables and Mann–Whitney U test for continues variables.