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. 2021 Jun 15;11(6):2802–2820.

Figure 7.

Figure 7

Hypothetical model. Hsa-miR-19b-3p and hsa-miR-101-3p are induced in prostate tumors from patients compared to NAT, and in tumors of metastatic patients versus tumors of non-metastatic patients. Both miRNAs are increased in the bloodstream of PCa patients compared to those without cancer. Hsa-miR-19b-3p negatively regulates the expression of genes involved in the proteoglycan in cancer and focal adhesion pathways, which could contribute to a more aggressive tumor phenotype.