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. 2021 Jul 7;11:14001. doi: 10.1038/s41598-021-93430-2

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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UL16 protein binding to ANT2. (A) Coimmunoprecipitation assay demonstrates that Flag-UL16 and ANT2 coexpression in HUVEC cells (Image J1 software http://imagej.nih.gov/ij/plugins/). (B, C) Immunoblots and cellular ATP levels of ANT2 at 24 h, after pSINsi-UL16 transfection. (D) ATP levels in 20 h of HUVEC cells, between mock cell, siRNA (control siRNA) transfection group, UL16 transfection group, and ANT2 siRNAs transfection group. The data shown in each panel are representative of three independent experiments.