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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: Prog Retin Eye Res. 2021 Jan 8;83:100941. doi: 10.1016/j.preteyeres.2021.100941

Figure 11. UCP2 Protects CNS neurons from degeneration.

Figure 11.

A. Stereological quantification of dopamine cell number revealed that UCP2 TG mice had significantly (p<0.05) more surviving neurons than their WT littermates after MPTP treatment. *Significant with respect to wild-type controls. B. Epileptic seizure-induced cell death is diminished in hUCP2- expressing mice. Cell death in the CA1 area of the hippocampus was significantly reduced in surviving transgenic animals compared with surviving wild-type littermates 24 h after seizures. Figure adapted form refs 160 and 11.