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The effect of TSA on osteoblasts viability and epigenetic functionality. TSA caused a time‐dose dependant effect on osteoblast a) morphology (day 3) and b) metabolic activity. Treatment with TSA altered osteoblast c) HDAC activity and d) H3K9 histone acetylation in a time‐dose dependent manner. Data are expressed as mean ± SD (n = 3). *P ≤ 0.05, **P ≤ 0.01 and ***P ≤ 0.001. Scale bar = 100 µm
