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. 2021 Jun 24;12:650884. doi: 10.3389/fneur.2021.650884

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Copyright © 2021 Hwang, Park, Park, Lee, Oh and Suh.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Three-dimensional magnetic resonance imaging of rat cochlea at 2 h after intratympanic (IT) gadolinium (Gd)-diethylenetriamine pentaacetic acid (DTPA) injection. Although the scala tympani (ST) and scala vestibuli (SV) were enhanced by Gd, the scala media (SM) was not. Based on this enhancement pattern, we were able to identify the three compartments (ST, SV, and SM) and the three turns (apical, middle, and basal) of the cochlea. The signal intensity (SI) in each compartment in each turn was quantified for further comparison between the vehicles.