Table 4.
The concentration of inflammatory biomarkers in the circulation of non-HF control individuals and HFpEF patients.
| Non-HF | HFpEF | p-Value | |
|---|---|---|---|
| (n = 42) | (n = 30) | ||
| Laboratory | |||
| TNFα, pg/ml | 10.20 (2.42, 12.74) | 12.38 (5.75, 19.70) | < 0.05 |
| IL-1β, pg/ml | 3.46 (2.53, 4.97) | 17.93 (5.45, 21.93) | < 0.05 |
| IL-6, pg/ml | 1.72 (1.09, 2.18) | 3.79 (1.25, 7.53) | < 0.05 |
| IL-10, pg/ml | 0.26 (0.12, 0.35) | 0.38 (0.22, 1.16) | < 0.05 |
| MMP9, ng/ml | 270.1 (180.2, 390.6) | 621.3 (302.5, 915.4) | < 0.05 |
| sICAM, ng/ml | 401.5 (257.2, 536.8) | 583.2 (337.6, 721.5) | < 0.05 |
| NE, ng/ml | 83.28 (60.5, 134.3) | 121.5 (90.6, 374.0) | < 0.05 |
Data are given as median (IQR). Mann-Whitney test for unpaired observations was applied, and p < 0.05 was considered to indicate statistical significance.
IL, interleukin; MMP9, matrix metalloproteinase 9; NE, neutrophil elastase; sICAM-1, soluble intercellular adhesion molecule-1; TNFα, tumor necrosis factor alpha.