Table 2.
BRONJ Patients N = 14 (%) | |
---|---|
Predisposing factors | |
○ Spontaneous | 9 |
○ Dental Extraction | 5 |
MM status at BRONJ onset | |
○ CR | 5 |
○ PR | 4 |
○ PD | 5 |
MM Therapy at BRONJ onset | |
○ Lenalidomide | 8 |
○ Carfilzomib | 3 |
○ Other | 3 |
○ Zoledronic acid | |
▪ Monthly | 9 |
▪ 3 months | 5 |
Symptoms | |
○ Mild (exam finding) | 10 |
○ Severe pain, swelling | 4 |
AAOMS staging | |
○ 1 | 1 |
○ 2 | 11 |
○ 3 | 2 |
Location of the lesions | |
○ Mandible | 11 |
○ Maxilla | 1 |
○ Both | 2 |
BRONJ Outcome | |
○ Healed | 9 |
○ Non-healing | 5 |
○ Healed and recurred | 3 |
BRONJ, bisphosphonate related osteonecrosis of the jaw; AAOMS, American Association of Oral and Maxillofacial Surgeons.