Table 2.
Illustration of Core network DEGs in Validation datasets.
| MvsN | PvsN | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| DEGs | GSE40367 | GSE50760 | GSE41258 | GSE144259 | GSE89393 | DEGs | TCGA | GSE50760 | GSE41258 | GSE144259 | GSE89393 | |
| liver-normal | liver-normal | liver-normal | lung-normal | liver-normal | liver-normal | primary-normal | ||||||
| ETHE1 | Down | Down | Down | Down | Down | Down | SGK1 | Down | Down | Down | Down | Down |
| DARS | Up | Up | Up | Up | Up | Up | EIF2S2 | Up | Up | Up | Up | Up |
| TMEM131 | Down | Down | Down | Down | Down | Down | TRIB3 | Up | Up | Up | Up | Up |
| TST | Down | Down | Down | Down | Down | Down | DARS | Up | Up | Up | Up | Up |
| LGALS4 | Down | Down | Down | Down | Down | Down | RFC3 | Up | Up | Up | Up | Up |
| TRIB3 | Up | Up | Up | Up | Up | Up | ETHE1 | Down | Down | Down | Down | Down |
| COL5A2 | Down | Up | Up | Up | Up | Down | TOP2A | Up | Up | Up | Up | Up |
| COL4A1 | Down | Up | Up | Up | Up | Down | CKS2 | Up | Up | Up | Up | Up |
| PTP4A1 | Down | Down | Down | Down | Down | Down | SORD | Up | Up | Up | Up | Up |
| COL1A2 | Up | Up | Up | Up | Up | Up | PSMA7 | Up | Up | Up | Up | Up |
| SORD | Up | Up | Up | Up | Up | Up | GPX3 | Down | Down | Down | Down | Down |
| SQOR | Down | Down | Down | Down | Down | Down | MAD2L1 | Up | Up | Up | Up | Up |
| OAS1 | Down | Down | … | Down | Down | Down | SQOR | Down | Down | Down | Down | Down |
| TRIM31 | Down | Down | Down | Down | Down | Down | TST | Down | Down | Down | Down | Down |
| TWF1 | Down | Down | … | Down | … | Down | GINS1 | Up | Up | Up | Up | Up |
| MvsP | LGALS4 | … | Down | Down | Down | Down | ||||||
| DEGs | GSE40367 | GSE50760 | GSE41258 | GSE144259 | GSE89393 | PTP4A1 | Up | Down | Down | Down | Down | |
| liver-primary | liver-primary | liver-primary | lung-primary | liver-primary | liver-primary | PLAGL2 | … | Up | Up | Up | Up | |
| ETHE1 | Down | Down | … | Down | Down | Down | COL1A2 | Down | Up | Up | Up | Up |
| ATF5 | … | Up | Up | … | Up | … | CTSH | … | Up | Up | Up | Up |
| CDC6 | Down | Up | Down | Down | Down | Down | MT2A | Down | Down | Down | Down | Down |
| TMPO | Down | … | … | Down | Down | Down | COL5A2 | Down | Up | Up | Up | Up |
| P4HA1 | Up | Up | Up | Up | Up | Up | ||||||
Up means gene was upregulated and Down means gene was Downregulated. MvsN contains all the metastatic versus normal analyses, PvsN contains all the primary versus normal analyses and MvsP contains all the metastatic versus primary analyses. Some genes are present in more than one analysis. The expression status for the genes in green rows are similar in all datasets regardless of empty cells. In the yellow rows only one dataset is different from the others and in the white rows genes exhibited a heterogeneous expression status in different datasets. Green rows illustrate a similar expression in all datasets.