Figure 3.

The effects of kaempferol and EGCG on the expression of apoptotic and anti-apoptotic genes in leukemia HL60 cells. The cells were treated for five days with kaempferol, EGCG, or ATRA, and the expression of apoptotic (CASP3, CASP9, CASP8, P21, PTEN and Bax) and anti-apoptotic (PI3K, AKT and Bcl2) genes was checked by real-time PCR. The data are expressed as the mean±SEM of three independent experiments performed in triplicate. *p<0.05, **p<0.01, and ***p<0.001 vs. the untreated control cells