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. 2021 Jul 8;116:37–46. doi: 10.1016/j.jhin.2021.06.011

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Elements considered in the risk of bias evaluation. The rectangles labelled RQ1 and RQ2 show the parts of the model that were explored by research question 1 and research question 2, respectively. The orange area of overlap between these rectangles indicates the intersection of the foci of the two research questions in relation to aerosol production. RQ1: Does evidence suggest that medical procedures which induce coughing or involve respiratory airway suctioning result in infectious aerosol production? RQ2: If yes, what is the associated risk of transmission of SARS-CoV-2? The grey box labelled ‘Not covered in the literature’ refers to the evidence base when the searches were conducted (October 2020). AG, aerosol-generating; AGP, aerosol-generating procedure; AGB, aerosol-generating behaviour; PPE, personal protective equipment.