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. 2021 Jun 24;12:648250. doi: 10.3389/fimmu.2021.648250

Table 2.

Drug-likeness (Lipinski rule of five) for andrographolide.

Lipinski rule of five
Property Desired value Andrographolide
Mol Wt. <500 350.46
H-Bond Donors <5 3
H-Bond Acceptors <10 5
Rotatable Bonds <10 3
Lipophilicity (LogP) <5 1.96