Table 5. Multivariate analysis of risk factors of immune-related adverse events (irAEs). Combination therapy was not the independent risk factor for stomatitis and bone marrow failure.
| Variable | Stomatitis | Bone marrow failure | |||
|---|---|---|---|---|---|
| Adjusted OR (95% CI) | P value | Adjusted OR (95% CI) | P value | ||
| Combination therapy | 1.82 (0.75–3.98) | 0.203 | 1.05 (0.40–2.73) | 0.926 | |
| Comorbidity | 0.94 (0.46–2.15) | 0.987 | 0.81 (0.25–2.70) | 0.734 | |
| Disease progression | 1.73 (1.15–2.60) | 0.008 | 0.31 (0.10-1.01) | 0.052 | |
| Stage IV | 0.70 (0.32–1.53) | 0.371 | 0.54 (0.19–1.54) | 0.246 | |
| Chemotherapy | 1.83 (1.16–2.87) | 0.009 | 10.25 (5.55–18.96) | <0.001 | |
CI, confidence interval.