Table 4.

Rheumatoid nodules and Rheumatoid factor association with peptide reactivity.

		Rheumatoid Nodules				Rheumatoid Factor
		(n = 30/180)				(n = 122/161)
		NO	YES	Odds Ratio	p	NO	YES	Odds Ratio	p
		(n)	(n)	[CI 95%]		(n)	(n)	[CI 95%]
Rheumatoid Factor (n=122/161)	NO	35	3	2.89 [0.88 – 9.52]	0.08
	(n)
	YES	97	24
	(n)
β60-74cit	NO	63	11	1.25 [0.55 – 2.69]	0.59	15	54	0.79 [0.37 – 1.68]	0.52
	(n)
	YES	87	19			24	68
	(n)
α36-50cit	NO	130	26	0.23 [0.33 – 2.89]	0.99	36	102	2.35 [0.70 – 7.83]	0.17
	(n)
	YES	20	4			3	20
	(n)
α621-635cit	NO	81	19	0.68 [0.32 – 1.53]	0.35	25	68	1.42 [0.66 – 2.88]	0.36
	(n)
	YES	69	11			14	54
	(n)
α501–515cit**	NO	55	6	2.32 [0.95 – 5.80]	0.08**	18	33	2.31 [1.10 – 4.78]	0.026
	(n)
	YES	95	24			21	89
	(n)
α171–185cit	NO	37	7	1.08 [0.45 – 2.75]	0.88	11	30	1.21 [0.56 – 2.68]	0.65
	(n)
	YES	113	23			28	92
	(n)
Number of specificity	≤ 3	119	21	1.65 [0.69 – 3.78]	0.26	35	93	2.73 [0.91 – 7.61]	0.07
	> 3	31	9			4	29

N, number of patients; NS, not significant.

**High level anti-α501–515cit (T2-T3 tertiles combined) was significantly associated with rheumatoid nodules, OR =2.71 [1.00 – 7.16], p= 0.044. 79/184 patients had high level anti- α501–515cit, among them 18 patients had rheumatoid nodules, 61/184 patients did not have high level anti- α501–515cit, of whom 6 patients had rheumatoid nodules.

Bold values are the one which are important regarding the text of the article.