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. 2021 Jun 24;9:683719. doi: 10.3389/fpubh.2021.683719

Table 1.

Summary of epidemiological investigations on microcystins and liver disease.

Authors Country Design Environmental toxin Finding
Ueno et al. (23) China Epidemiological survey Microcystin MC detection in drinking water sources correlates with a high PLC incidence
Fleming et al. (25) USA Pilot ecological study Microcystin Residential proximity to surface water drinking sources increases HCC risk
Chen et al. (75) China Longitudinal study Microcystin Concurrent detection of serum MCs and liver enzymes indicate hepatocellular damage in fishermen
Svirčev et al. (24) Serbia Descriptive epidemiological method Microcystin Significant and persistent blooms correlate with PLC mortality and incidence
Zheng et al. (26) China Case-control study Microcystin Serum MC detection in patients link to HCC risk