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. 2021 Jun 24;14:681868. doi: 10.3389/fnmol.2021.681868

Figure 2.

Figure 2

Astrocytosis in the spinal cord of 24–30 weeks old SOD1-G93A/low mice. Female and male 24, 27, and 30 weeks old SOD1-G93A/low mice were evaluated for glial fibrillary acidic protein (GFAP) expression (A–C) in the cervical (A), thoracic (B), and lumbar (C) ventral horn compared to ntg littermates. Two-way ANOVA with Tukey's and Sidak's multiple comparison post hoc test; n = 4 per group. Mean + SEM. */#p < 0.05, ***p < 0.001. *Differences between genotypes; #differences between age groups. (D) Representative images of GFAP labeling in the thoracic spinal cord of 24, 27, and 30 weeks old male SOD1-G93A/low mice compared to ntg littermates.