Skip to main content
. 2021 Jun 24;11:680190. doi: 10.3389/fonc.2021.680190

Table 3.

Associations between adipose tissue distribution parameters and disease-specific survival by multivariate Cox analysis in patients with gastric cancer.

High SAT percent High VAT percent VAT/SAT ratio
HR (95%CI) P value HR (95%CI) P value HR (95%CI) P value
Adipose tissue distribution parameter 0.59 (0.36, 0.96) 0.032 1.68 (1.06, 2.68) 0.028 1.99 (1.19, 3.34) 0.009
Overweight/obesity 0.56 (0.34, 0.91) 0.021 0.55 (0.34, 0.91) 0.019 0.55 (0.33, 0.90) 0.017
Age (>65 years) 1.56 (1.13, 2.17) 0.008 1.54 (1.11, 2.14) 0.010 1.56 (1.12, 2.16) 0.008
Female 0.98 (0.69, 1.4) 0.929 0.93 (0.66, 1.32) 0.696 0.95 (0.67, 1.35) 0.794
T category
 T1 1 1 1
 T2 2.51 (0.88, 7.13) 0.085 2.49 (0.87, 7.08) 0.880 2.49 (0.88, 7.07) 0.087
 T3 2.77 (0.52, 14.66) 0.230 2.86 (0.54, 15.09) 0.216 2.81 (0.53, 14.77) 0.223
 T4a 3.59 (1.45, 8.88) 0.006 3.61 (1.46, 8.95) 0.006 3.63 (1.47, 8.95) 0.005
 T4b 10.44 (3.35, 32.47) <0.001 10.39 (3.34, 32.31) <0.001 10.73 (3.47, 33.20) <0.001
N category
 N0 1 1 1
 N1 2.38 (1.21, 4.68) 0.012 2.31 (1.17, 4.57) 0.016 2.33 (1.18, 4.60) 0.015
 N2 2.45 (1.3, 4.61) 0.005 2.35 (1.25, 4.43) 0.008 2.42 (1.29, 4.54) 0.006
 N3a 6.74 (3.63, 12.51) <0.001 6.55 (3.53, 12.14) <0.001 6.65 (3.60, 12.30) <0.001
 N3b 9.01 (4.47, 18.15) <0.001 8.65 (4.3, 17.4) <0.001 8.96 (4.46, 18.01) <0.001
Chemotherapy 0.82 (0.54, 1.25) 0.356 0.81 (0.54, 1.23) 0.329 0.82 (0.54, 1.24) 0.340

BMI, body mass index; SAT, subcutaneous adipose tissue; VAT, visceral adipose tissue; HR, hazard ratios; CI, confidence interval.

Bold values represent statistically significant differences (P < 0.05).