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. 2021 Jun 24;12:661306. doi: 10.3389/fgene.2021.661306

TABLE 2.

Univariate and multivariate Cox regression analyses of clinical characteristics and risk score in GSE62254.

Univariate Cox Multivariate Cox
regression
regression
Characteristics Number Hazard Ratio (95%CI) p-value Hazard Ratio (95%CI) p-value
Age 298 1.011 (0.996–1.026) 0.157 1.028 (1.012–1.044) 0.001
Gender
 Male/Female 197/101 0.917 (0.656–1.282) 0.611
Tumor stage
II/I 96/30 1.955 (0.759–5.034) 0.165 1.678 (0.649–4.338) 0.285
III/I 95/30 4.064 (1.623–10.176) 0.003 2.669 (1.030–6.920) 0.043
IV/I 77/30 9.737 (3.907–24.265) <0.001 4.837 (1.755–13.328) 0.002
T
T3-4/T1-2 112/186 2.365 (1.719–3.255) <0.001
N
N1-3/N0 260/38 2.847 (1.450–5.589) 0.002
M
M1/M0 27/271 3.806 (2.460–5.888) <0.001
Number of lymph nodes examined 298 0.987 (0.976–0.998) 0.023
number of positive lymph nodes 298 1.072 (1.056–1.087) <0.001
LNR 298 25.430 (13.312–48.578) <0.001 7.030 (2.803–17.631) <0.001
Risk score 298 5.205 (2.750–9.853) <0.001 4.059 (2.097–7.855) <0.001