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. 2021 Jun 24;12:675146. doi: 10.3389/fimmu.2021.675146

Figure 2.

Figure 2

Primary melanomas (PT): TLS phenotypes, density and spatial distribution. (A) Prevalence of TLS in primary tumor samples. (B) Relative prevalence of TLS phenotypes in primary tumors. (C) Density of early TLS over intra- and extratumoral compartments of primary tumors. In all boxplots, lower and upper hinges correspond to the first and third quartiles, center line to the median. Upper and lower whisker extend from the hinge to the largest value no further than 1.5 times the interquartile range. Values outside this range are shown as outliers (black circles). Individual patient values are shown as black dots. TLS, tertiary lymphoid structures; GC, germinal center.