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. 2021 Jun 24;11:629823. doi: 10.3389/fonc.2021.629823

Table 1.

Baseline characteristics of the study population.

Characteristics All patients Training sample Validation sample P value
Number 411 288 123
Gender, N (%) 0.492
 male 230 (56.0%) 158 (54.9%) 72 (58.5%)
 female 181 (44.0%) 130 (45.1%) 51 (41.5%)
Age, mean ± SD 58.4 ± 10.6 58.8 ± 10.2 57.4 ± 11.4 0.239
Type of tumor, N (%) 0.667
 rapid 191 (46.5%) 138 (47.9%) 53 (43.1%)
 moderate 164 (39.9%) 112 (38.9%) 52 (42.3%)
 slow 56 (13.6%) 38 (13.2%) 18 (14.6%)
Tumor location, N (%) 0.906
 cervical 49 (11.9%) 33 (11.5%) 16 (13.0%)
 thoracic 206 (50.1%) 145 (50.3%) 61 (49.6%)
 lumbar 156 (38.0%) 110 (38.2%) 46 (37.4%)
Number of spinal metastases, N (%) 0.356
 single 161 (39.2%) 117 (40.6%) 44 (35.8%)
 multiple 250 (60.8%) 171 (59.4%) 79 (64.2%)
BMI (kg/m2), N (%) 0.991
 < 18.5 13 (3.2%) 9 (3.1%) 4 (3.3%)
 18.5-30 349 (84.9%) 245 (85.1%) 104 (84.6%)
 > 30 49 (11.9%) 34 (11.8%) 15 (12.2%)
Surgical procedure, N (%) 0.351
 type 1 68 (16.5%) 43 (14.9%) 25 (20.3%)
 type 2 319 (77.6%) 229 (79.5%) 90 (73.2%)
 type 3 24 (5.8%) 16 (5.6%) 8 (6.5%)
Preoperative radiotherapy, N (%) 0.426
 yes 246 (59.9%) 176 (61.1%) 70 (56.9%)
 no 165 (40.1%) 112 (38.9%) 53 (43.1%)
Preoperative chemotherapy, N (%) 0.441
 yes 239 (58.2%) 171 (59.4%) 68 (55.3%)
 no 172 (41.8%) 117 (40.6%) 55 (44.7%)
Visceral metastases, N (%) 0.462
 no 100 (24.3%) 73 (25.3%) 27 (22.0%)
 yes 311 (75.7%) 215 (74.7%) 96 (78.0%)
Blood loss (liters), mean ± SD 1.3 ± 1.1 1.2 ± 0.9 1.3 ± 1.3 0.497
Preoperative Frankel score, N (%) 0.693
 A-C 109 (26.5%) 78 (27.1%) 31 (25.2%)
 D-E 302 (73.5%) 210 (72.9%) 92 (74.8%)
Blood transfusion, N (%) 0.194
 yes 177 (43.1%) 130 (45.1%) 47 (38.2%)
 no 234 (56.9%) 158 (54.9%) 76 (61.8%)
Charlson comorbidity index, N (%) 0.131
 6 63 (15.3%) 42 (14.6%) 21 (17.1%)
 7 117 (28.5%) 75 (26.0%) 42 (34.1%)
 ≥8 231 (56.2%) 171 (59.4%) 60 (48.8%)
Operative time (hours), mean ± SD 4.0 ± 1.4 4.0 ± 1.3 4.1 ± 1.6 0.759