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. 2021 Jun;13(6):3721–3730. doi: 10.21037/jtd-21-193

Table 6. Management of Primary Spontaneous Pneumomediastinum patients.

Study Antibiotics (%) Admission (%) Mean LOS (days)
Abolnik et al. 1991 NR 100 6.3
Kaneki et al. 2000 NR 100 NR
Gerazounis et al. 2003 NR NR NR
Jougon et al. 2003 NR 100 4
Koullias et al. 2004 100 50 2
Weissberg & Weissberg 2004 NR 100 3.5
Campillo-Soto et al. 2005 NR 100 8.6
Newcomb & Clarke 2005 NR 100 2
Freixinet et al. 2005 NR 100 3.2
Macia et al. 2007 NR 100 5
Mondello et al. 2007 NR NR 6
Caceres et al. 2008 NR NR 3
Al-Mufarrej et al. 2008 58.8 100 NR*
Takada et al. 2008 76 96 7.8
Perna et al. 2010 NR 100 3.5
Ryoo 2012 0* 78 3.5
Okada et al. 2014 20 50 7
Bakhos et al. 2014 NR 78 1.8
Ebina et al. 2017 5.9 32 3.4
AVE ± std dev [n] 43%±40.8% [6] 86.5%±22.6% [18] 4.4%±2.1% [18]

**, for patients with no other co-morbidities, the length of hospital stay ranged from 23–72 hours (average 40.5 hours). Patients admitted with significant dehydration, asthma exacerbation, or drug intoxication had longer hospital stays (5–11 days with average of 7 days).