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. 2021 Jun;13(6):3846–3864. doi: 10.21037/jtd-20-2360

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2021 Journal of Thoracic Disease. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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The evolution of smart inhalers over time. (A) Nebulizer Chronolog (68); (B) Aerosol Actuation Counter (MDI) (69); (C) Doser (MDI) (70,71); (D) Smart Mist (MDI) (69,72); (E) MDILog (MDI) (69,73); (F) SmartTouch for Symbicort (MDI) (69,70); (G) SmartInhaler Tracker (pMDI) (69); (H) SmartTrack (MDI) (69,74); (I) Inspiromatic (DPI) (75); (J) Prohaler (DPI) (76); (K) Updated SmartTouch for Symbicort (MDI) (77-79); (L) eMDI (pMDI) (80); (M) Turbu+ (MDI) (81); (N) Electronic Breezhaler (DPI) (82); (O) Hailie for Flovent, available for multiple devices (Ventolin, ProAir, Seretide) (MDI) (83,84); (P) CareTRx (MDI) (69,85); (Q) Propeller sensor Diskus (DPI) (86,87); (R) HeroTracker (DPI & MDI) (88); (S) GSK Elipta inhaler (propeller sensor) (DPI) (89,90); (T) Propeller sensor for Neohaler (and Breezhaler) (DPI) (91,92) ; (U) Findair (MDI) (93); (V) Propeller sensor for Symbicort (pMDI) (94); (W) Enerzair Breezhaler (DPI) (95); (X) I-neb (Nebulizer) (96,97); (Y) Verihaler (MDI) (98); (Z) T-haler (MDI) (99); (A1) RSO1 (DPI) (100); (B1) INCA (DPI) (101); (C1) Respiro Sense diskus (DPI), also available for Easyhaler, Zephir, Handihaler and Elipta (102); (D1) Inspair (pMDI) (103); (E1) Pneumahaler (Soft mist inhaler) (104); (F1) Proair Digihaler (mDPI) (105). *, FDA approved smart inhalers; **, Smartdisk (DPI), Smartturbo (DPI), Smartflow (pMDI), Smartmat (SMI) are devices from the same company but not FDA approved. They all have reminder and feedback function and count the number of inhalation and record time and date, but they are suited for different inhaler devices. This company is now Hailie; #, do predict exacerbations and does not give reminders.