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. 2021 Jun;13(6):3669–3679. doi: 10.21037/jtd-21-882

Figure 2.

Figure 2

miR-155-5p targets and negatively regulates FGF9 expression. (A) miR-155-5p levels in the lung squamous cell carcinoma (SCC) cell lines H2170, H1703, and H520 and the normal bronchial epithelial cell line BEAS-2B were measured by fluorescence quantitative PCR. (B) FGF9 levels in the lung squamous cell carcinoma (SCC) cell lines H2170, H1703, and H520 and the normal bronchial epithelial cell line BEAS-2B were measured by fluorescence quantitative PCR. (C) The binding site of miR-155-5p and FGF9 was predicted. (D) The miR-155-5p and FGF9 3’-UTR region binding site was identified through luciferase reporter gene detection. (E) Western blot was performed to examine how inhibiting miR-155-5p affects FGF9 expression. *P<0.05.