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. 2021 Jun;13(6):3518–3528. doi: 10.21037/jtd-21-340

Table 4. Correlation between preoperative basic patient information and partial pathological response.

Parameters MPR (N=16) Non-MPR (N=22) P value
Age
   Mean ± SD 64.75 (3.60) 59.55 (1.40) 0.019 [1]*
Gender
   Male 15 21 1.000 [2]
   Female 1 1
Smoking history
   Yes 7 15 0.132 [3]
   No 9 7
Drinking history
   Yes 6 11 0.444 [3]
   No 10 11
BMI
   <18.5 1 2 1.000 [2]
   ≥18.5 15 20
Tumour location
   Proximal third 0 3 0.240 [2]
   Middle third 11 10
   Distal third 5 9
Interval from completion of NACI to surgery (weeks) 4.94(0.98) 6.27(0.61) 0.199 [1]
Neoadjuvant therapy regimens
   Cis-platinum + Paclitaxel + Camrelizumab 4 4 0.341 [2]
   Carboplatin + Paclitaxel + Camrelizumab 1 3
   Cis-platinum + Paclitaxel + Pembrolizumab 6 10
   Cis-platinum + Paclitaxel + Sintilimab 3 0
   Carboplatin + Paclitaxel + Pembrolizumab 2 3
   Paclitaxel + Nedaplatin + Sintilimab 0 2
Chemotherapy course + immunotherapy course
   <4 2 4 1.000 [2]
   ≥4 14 18
Immunotherapy regimen
   Camrelizumab 5 7 0.732 [2]
   Pembrolizumab 8 13
   Sintilimab 3 2
Immunotherapy course
   <2 2 3 1.000 [2]
   ≥2 14 19
Staging
   III 12 19 0.425 [2]
   IVA 4 3

[1]: P value is calculated by t-test; [2]: P value is calculated by Fisher exact test; [3]: P value is calculated by chi-squared test. Main Pathological Reaction, MPR; P>0.05 NS, *P<0.05.