Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Jul 8;10(7):e1311. doi: 10.1002/cti2.1311

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 The Authors. Clinical & Translational Immunology published by John Wiley & Sons Australia, Ltd on behalf of Australian and New Zealand Society for Immunology, Inc

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

PMC Copyright notice

Depletion of neutrophils ameliorates disease symptoms in mice with DSS‐induced colitis. (a) Experimental schedule of neutrophil depletion in a murine model of DSS‐induced colitis. Ly‐6G depletion antibodies were injected intraperitoneally for five consecutive days. (b) Representative flow cytometry plots of neutrophils in the colon at day 5 post‐induction with DSS. (c) The percentage of total neutrophils in the colon at day 5 post‐induction with DSS. (d, e) A representative picture of colons (d) and colon length (e). (f, g) Photomicrographs (f) of H&E‐stained histological sections of the proximal colon (scale bar: 100 μm), and histology score (g) at day 5 post‐induction with DSS. (h) The percentage of GM‐CSF⁺ NCR^‐ ILC3s in the colon at day 5 post‐induction with DSS. Data are presented as mean ± SEM (one‐way ANOVA). Data are representative of two independent experiments with n = 5 per group. *P < 0.05, **P < 0.01, ***P < 0.005 and ****P < 0.001, and ns, not significant (P > 0.05).