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. 2021 Jun 24;9:671961. doi: 10.3389/fpubh.2021.671961

Table 7.

Key characteristics of the insulin glargine market (100 IU/ml) among European countries.

Bio Usage (%) Price difference at launch (Bio vs. Originator) % Price difference originator over time (%) Latest price difference (Bio vs. Originator—%) % Gla-300 (latest)
Albania NA NA −32.2 NA 45.3
Bosnia and Herezegovina 6.2 0.0 −11.3 −7.9 52.1
Bulgaria 11.0 −4.7 −10.8 −5.7
Catalonia 12.4 −23.1 −23.1 Similar 28.1
Estonia 0.69 −16.4 −24.9 55.4
Hungary 24.6 −28.2 −21.1 −1.6 58.0
Italy 25.0 −52.3 −24.0 30.4
Latvia NA NA −14.4 NA 51.4
Lithuania 26.5 −12.3 −21.1 0.0 39.0
Poland 44.8 −24.6 −31.1 −0.2 37.1
Scotland 19.5 −18.1 −9.0 −7.5 9.3
Slovenia 15.7 −22.9 −20.3 −9.9

NB: Bio usage, % insulin glargine biosimilar vs. total insulin glargine 100 IU/ml on a DDD basis; Orig, Originator; Gla-300, TOUJEO 300 IU/ml on a DDD basis; Blanks represent no data available; NA, Biosimilars not yet launched; Latest price difference either 2019 or 2020 depending on available data; price differences calculated on a DDD basis using local currencies.