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. 2021 Jun 24;8:597630. doi: 10.3389/fvets.2021.597630

Table 3.

Epidemic characteristics, mean generation time, and R0 in two models by HPAI subtype H5N1, H5N8, and H5N6.

Subtype Average Average Cases Chicken (%) Duck (%) Etc. (%) Mean generation R0 by EG Method R0 by ML Method
epidemic days number of farms per day time (days) (95% CI) (95% CI)
H5N1 86.0 69.0 0.802 41.7 (60.4) 26.0 (37.7) 2.0 (2.9) 4.80 (4.23–5.38) 1.96 (1.48–2.39 1.69 (1.10–2.28)
H5N8 143.8 107.8 0.750 23.5 (21.8) 80.0 (74.2) 4.3 (3.9) 7.58*(6.63–8.46) 1.49 (1.19–1.79) 1.60 (0.97–2.23)
H5N6 108.0 181.0 1.676 100.0 (55.2) 77.0 (42.5) 4.0 (2.2) 5.09 (4.44–5.74) 1.14 (0.76–1.51) 1.49 (0.94–2.04)

EG, exponential growth; ML, maximum likelihood estimation; CI, confidence interval.

*

Mean generation time of subtype H5N8 is significantly longer than subtype H5N1 (P = 0.03).