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. 2021 Jul 7;8(1):e000759. doi: 10.1136/bmjresp-2020-000759

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.

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Scatter plot of the single nucleotide polymorphism (SNP) effect on lung function trait and SNP effect on Alzheimer’s disease. Each point on the graph represents the SNP-outcome association plotted against the SNP-exposure association. Bars indicate 95% CIs. Coloured lines represent analysis method used. This shows no effect of lung function on Alzheimer’s disease. Mendelian randomisation (MR) Egger intercept is close to zero indicating no unbalanced directional pleiotropy.