Table 3.
Characteristics of patient with low flow/low gradient AS
| Low-flow, low-gradient AS | Normal-flow, high-gradient | Significance (p value) |
|
| n=10 | n=90 | ||
| AVA baseline (cm2) | 0.73±0.14 | 0.76±0.15 | 0.571 |
| AV mean gradient baseline (mm Hg) | 26.2±3.8 | 50.3±11.7 | <0.001 |
| PASP baseline (mm Hg) | 39.3±12.7 % |
39.5±11.8 % |
0.966 |
| LVEF baseline (%) | 36.9±6.7 | 55.4±7.3 | <0.001 |
| LVEDD baseline (mm) | 55.3±9.1 | 49.8±5.4 | 0.006 |
| LVESD baseline (mm) | 43.8±10.7 | 32.6±6 | <0.001 |
| IVSd (mm) | 11.6±1.3 | 13.1±1.6 | 0.006 |
| TAPSE baseline (mm) | 18.8±2.4 | 22±2.6 | 0.005 |
| E/A | 0.8±0.6 | 0.7±0.3 | 0.501 |
| E/E‘ average | 15±6 | 13.5±2.8 | 0.234 |
| EuroSCORE II baseline (%) | 12.0±13.4 | 5.1±3.4 | <0.001 |
| LAS, pre-TAVR | 10.6±4.8 | 15.6±5.9 | 0.011 |
| ΔLAS | −1.08±4.46% | 0.36±4.95% | 0.407 |
| LAVi, pre-TAVR (mL/m2) | 49.7±22.5 | 48.1±13.1 | 0.791 |
| ΔLAVi | −8.1±15.7 | −11.6±17.4 | 0.672 |
AS, aortic stenosis; AV, aortic valve; AVA, aortic valve area; E/A, early-to-late diastolic flow ratio; E/E’, E-to-mean E’ ratio; IVSd, interventricular septal diameter diastolic; LAS, left atrial strain; LAVi, left atrial volume index; LVEDD, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESD, left ventricular end-systolic diameter; PASP, pulmonary artery systolic pressure; TAPSE, tricuspid annular plane excursion; TAVR, transcatheter aortic valve replacement.