Table 2.
Clinical and hormonal characteristics of infants with PWS at the time of ghrelin measurement during the first year of life according to their EOS status at the age of 4 years
| PWS infants who later developed EOS n = 8 | PWS infants who did not later develop EOS n = 29 | p value | |
|---|---|---|---|
| Sex—girls, n (%) | 3 (37.5) | 10 (34.5) | 1.000 |
| Age—month, median (IQR) | 6.1 (3.6–10.3) | 7.6 (4.8–9.1) | 0.912 |
| BMI—WHO z-score, median (IQR)a | − 1.8 (− 2.5– − 1.1) | − 1.1 (− 1.9–0.0) | 0.110 |
| Genetic subtype—deletion, n (%)a | 4 (50.0) | 12 (42.9) | 1.000 |
| IGF-1—z-score, median (IQR)b | − 2.1 (− 2.5– − 1.3) | − 1.1 (− 1.7– − 0.4) | 0.008 |
aOne non-scoliotic patient without data on height and unspecified genetic subtype
bTwo patients, one in each group, without data on IGF-1