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. 2021 Jul 7;21:495. doi: 10.1186/s12884-021-03946-8

Table 4.

Discontinuations, Conceptions, and Conceptions Leading to Live Births up to 24 Months After Beginning Natural Procreative Technology Treatment, by Characteristics of Couples Beginning Treatment

Couple Characteristics Couples n Exited Treatment, n (%) Conception, n (%) Live Births, n (%) Adjusted Conceptions, % P value Adjusted Live Births, % P value
All couples 370 209 (56) 116 (31) 66 (18) 39 29
Age, y 0.0216a 0.0438a
 <35 184 91 (49) 64 (35) 40 (22) 44 34
 ≥35 186 118(63) 52 (28) 26 (14) 33 23
Time trying for birth, y <0.001a <0.001a
 <1 97 45 (46) 40 (41) 24 (25) 52 38
 1-2.9 165 90 (55) 58 (35) 33 (20) 42 33
 ≥3 108 74 (69) 18 (17) 9 (8) 15 12
Had prior pregnancy 0.0129a 0.1299a
 Yes 169 92(54) 66(39) 35 (21) 52 36
 No 201 117 (58) 50 (25) 31 (15) 29 25
Had prior live birth 0.1040a 0.6249a
 Yes 99 58 (59) 34 (34) 18 (18) 54 35
 No 269 150 (56) 82 (30) 48 (18) 34 28
Received prior IVF 0.1861b 0.7490a
 Yes 21 16 (76) 4 (19) 2 (10) 30 20
 No 348 192 (55) 112 (32) 64 (18) 40 30
Received prior IUI 0.2305a 0.1836a
 Yes 49 33 (67) 11 (22) 5 (10) 21 15
 No 320 175 (55) 105 (33) 61 (19) 41 32
Physician 0.7869a 0.7506a
 Dr. Carpentier 316 179 (57) 98 (31) 56 (18) 39 30
 Dr. Rollo 54 30 (56) 18 (33) 10 (19) 40 27
Menstrual/fertility cycle charting 0.7551a 0.5753a
 Creighton Model 297 167 (56) 92 (31) 53 (18) 38 30
 Other 51 25 (49) 18 (35) 12 (24) 42 30
None/missing 22 17 (77) 6 (27) 1 (2) 49 10
BMI 0.0812b 0.0008b
 <25 154 83 (54) 54 (35) 38 (25) 45 40
 ≥25 121 65 (54) 34 (28) 12 (10) 31 16
Start date (tertiles) 0.0850a 0.8055a
 Dec 1990-June 2005 113 72 (64) 30 (27) 17 (15) 33 25
 June 2005-Mar 2010 130 58 (45) 44 (34) 31 (24) 42 34
 Mar 2010- Dec 2013 126 79 (63) 41 (33) 18 (14) 38 28

BMI body mass index, IUI intrauterine insemination, IVF in vitro fertilization

aFleming-Harrington weighted Renyi test

bAdjusted log-rank test