Table 1.

Top 30 up and downregulated genes in RANBP3L-deficient cells. Genes deregulated under isosmotic and hyperosmotic cell culture conditions are highlighted in bold

Top 30 upregulated genes				Top 30 downregulated genes
300 mosmol/kg		600 mosmol/kg		300 mosmol/kg		600 mosmol/kg
Gene	log2fold change	Gene	log2fold change	Gene	log2fold change	Gene	log2fold change
Pmp22	8.10	Unc5b	8.88	Hoxa9	−10.23	Zfp422	−9.10
Unc5b	7.56	Pmp22	7.65	Hoxa10	−9.91	Plagl1	−8.81
Tmem30b	7.35	Syt17	7.532	Epdr1	−9.39	Sh3gl2	−8.71
Syt17	6.84	Tmem30b	7.41	Hdgfrp3	−9.31	Hoxa10	−8.59
BC025446	6.19	Ica1	6.63	Zfp422	−9.28	Asb4	−8.44
Sparc	6.08	BC025446	6.55	Atp6v0e2	−8.80	Atp6v0e2	−8.44
Gnao1	5.85	Siglecg	6.47	Sh3gl2	−8.77	Galnt11	−8.38
Ica1	5.84	Gnao1	5.86	Phactr2	−8.64	Arrb1	−8.31
Lrrc32	5.66	Sparc	5.08	Eif5a2	−8.33	Hoxa9	−8.14
Gcnt3	5.55	Gcnt3	5.08	Galnt11	−7.95	Smoc1	−8.13
Acp5	5.51	Parvb	4.96	Inmt	−7.84	Phactr2	−7.98
Col4a1	5.35	Parm1	4.91	Smoc1	−7.73	Inmt	−7.86
Gstk1	5.32	Cntfr	4.85	Rnf217	−7.72	Epdr1	−7.80
Col4a2	5.20	Cbr1	4.84	Hebp2	−7.66	Aldh2	−7.57
Col4a3	5.15	Acp5	4.82	Aldh2	−7.49	Hdgfrp3	−7.57
Parm1	5.03	Col4a3	4.80	Ccdc91	−7.48	Ccdc91	−7.39
Siglecg	4.89	Parvg	4.77	Hoxd9	−7.46	Hebp2	−7.36
Itgb7	4.71	Sytl5	4.70	Hoxd8	−7.29	Neil3	−7.20
Gc	4.64	Mcpt8	4.63	Slc9a7	−7.26	Slc9a7	−7.14
Parvb	4.63	Gstk1	4.34	Sim1	−7.25	Adgra1	−7.08
Dmkn	4.62	Sftpd	4.24	Sipa1l2	−7.15	Sim1	−7.04
Cbr1	4.59	Myo7b	4.22	Bckdhb	−7.05	Zfhx4	−7.03
Myo7b	4.55	Serpinb9b	4.16	Tspan13	−7.02	Nrk	−7.00
Lrrc61	4.42	Dhrs9	4.16	Enox2	−6.96	Enox2	−6.99
Col4a4	4.36	Nid1	4.14	Asb4	−6.95	Kitl	−6.90
Bgn	4.34	Col4a2	4.13	Hoxd10	−6.73	Hoxd9	−6.85
Trex2	4.28	Ociad2	4.11	Prdm5	−6.68	Tspan13	−6.77
Inhba	4.18	C130073F10Rik	4.07	Pdlim1	−6.68	Eif5a2	−6.75
H60c	4.13	Col4a1	4.05	Nrk	−6.66	Hoxa7	−6.64
Glipr2	4.12	Lypd5	4.03	Hoxa7	−6.62	Sipa1l2	−6.61