Table 1.

Predictive performance of MTRX consensus scores on ClinVar variants

Score	TP rate	FP rate	Precision	Recall	AUC	MCC
MTR3D 5 Å	0.64	0.57	0.60	0.64	0.63	0.10
MTRv2 (21 codons)	0.64	0.55	0.60	0.64	0.64	0.12
MTRv1 (41 codons)	0.65	0.49	0.63	0.65	0.67	0.17
MTR3D + MTRv2 + MTRv1	0.77	0.30	0.77	0.77	0.85	0.49
MTRX	0.83	0.22	0.83	0.83	0.90	0.61