Table 3.

The effect of metcarbatone on Psma3, Psmb5 and Psmc6 gene expression in the kidney and blood

	Metcarbatone (mg/kg)	Kidney fold difference (SEM range)	Blood fold difference (SEM range)
Psma3	Control	1.00 (0.93–1.07)	1.00 (0.87–1.14)
	0.05	1.44 (1.34–1.54)*	0.76 (0.56–1.04)
	0.50	1.61 (1.50–1.74)**	0.53 (0.48–0.58)
Psmb5	Control	1.00 (0.93–1.08)	1.00 (0.84–1.18)
	0.05	1.51 (1.40–1.63)**	0.55 (0.39–0.77)
	0.50	1.69 (1.60–1.79)**	0.58 (0.51–0.67)
Psmc6	Control	1.00 (0.94–1.07)	1.00 (0.90–1.12)
	0.05	1.43 (1.34–1.54)*	0.83 (0.68–1.01)
	0.50	1.43 (1.34–1.53)*	0.60 (0.55–0.64)*

*P<0.05 and **P<0.01 compared to control