Table 4.

The effect of etcarbatone on Psma3, Psmb5 and Psmc6 gene expression in the kidney and blood

	Etcarbatone (mg/kg)	Kidney fold difference (SEM range)	Blood fold difference (SEM range)
Psma3	Control	1.00 (0.93–1.07)	1.00 (0.87–1.14)
	0.05	1.46 (1.29–1.65)*	0.61 (0.52–0.70)
	0.50	1.36 (1.29–1.43)*	0.85 (0.84–0.87)
Psmb5	Control	1.00 (0.93–1.08)	1.00 (0.84–1.18)
	0.05	1.82 (1.56–2.12)**	0.45 (0.37–0.55)
	0.50	1.61 (1.52–1.71)**	0.66 (0.59–0.74)
Psmc6	Control	1.00 (0.94–1.07)	1.00 (0.90–1.12)
	0.05	1.72 (1.52–1.95)**	0.79 (0.71–0.88)
	0.50	1.62 (1.53–1.72)**	1.07 (0.99–1.17)

*P<0.05 and **P<0.01 compared to control