Table 3.

Treatment outcomes and adverse events summary

Treatment Response	Number of patients (%) n = 34 (100)
Clinical response, PE / MRI	34 (100) / 34 (100)
Complete response	19 (56) / 16 (47)
Partial response	10 (29) / 9 (26.5)
Stable disease	2 (6) / 2 (6)
Progressive disease	0 (0) / 0 (0)
Not evaluable	3 (9) / 7 (20.5)
Histological response	27 (100)
No sign of disease	18 (67)
Disease present, clear margins	6 (22)
Disease present, extending to margins	3 (11)
Surgical response	27 (100)
No evidence of disease	24 (89)
Disease present	3 (11)
Adverse events	34 (100)
All AEs, any cause	33 (97)
Treatment‐related AE	33 (97)
Grade 3–4 AE	7 (21.2)
Treatment‐related grade 3–4 AE	3 (8.8)
Grade 5 AE	1 (2.9)
Treatment‐related grade 5 AE	0 (0)
Serious adverse event	8 (23.5)
Treatment‐related SAE	3 (8.8)
AS leading to treatment suspension	2 (5.9)
Deaths	1 (2.9)

Abbreviations: AE, adverse event; AS, adverse symptoms; MRI, magnetic resonance imaging; PE, physical exam; SAE, serious adverse event.