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. 2021 Jun 5;26(7):e1110–e1124. doi: 10.1002/onco.13797

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© AlphaMed Press; the data published online to support this summary are the property of the authors.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Kaplan‐Meier estimates of overall survival and progression‐free survival in patients in peripheral blood T‐cell subsets predicting prognosis over time. (A): CD4⁺ T cells and their subsets at baseline or during treatment were associated with OS and PFS. (B): CD8⁺ T cells and their subsets at baseline or during treatment were associated with OS and PFS. (C): CD4⁺CD25⁺Foxp3⁺ Treg cells and their subsets during treatment were associated with OS and PFS. The cutoff values were determined by calculated by the Youden index of the receiver operating characteristic curve. Log‐rank p values are reported from an unadjusted analysis. Abbreviations: BL, baseline; CI, confidence interval; CTLA4, cytotoxic T‐lymphocyte–associated protein 4; IFN‐r, Interferon‐gamma; Lymph, lymphocyte; OS, overall survival; PFS, progression‐free survival; RT, radiotherapy (during treatment); Treg, regulatory T cell.