Table 1.

Overall response rate in the overall population and in subgroups based on histology in Study 002

Overall response	All patients (n = 21), n (%)	SCC (n = 8), n (%)	NSCC (n = 13), n (%)
Best overall response a
CR	5 (23.8)	4 (50.0)	1 (7.7)
PR	10 (47.6)	2 (25.0)	8 (61.5)
SD	5 (23.8)	1 (12.5)	4 (30.8)
PD	0	0	0
NE	1 (4.8)	1 (12.5)	0
Number of subjects with overall response (CR + PR) (ORR [90% CI b]), %	15 (71.4 [51.3–86.8])	6 (75.0 [40.0–95.4])	9 (69.2 [42.7–88.7])

^a RECIST version 1.

^b The Clopper‐Pearson interval.

Abbreviations: CI, confidence interval; CR, complete response; NE, not evaluable; NSCC, nonsquamous cell carcinoma; ORR, overall response rate; PD, progressive disease; PR, partial response; SCC, squamous cell carcinoma; SD, stable disease.