Table 2.
Identifiable organisms and sites of infection.
| ALL and infantile ALL (n = 12) | AML (n = 4) | Relapse leukemia (n = 6) | SAA (n = 4) | Total | |
|---|---|---|---|---|---|
| IFI diagnosis, n )%( | |||||
| Proven | 6 (50.0) | 3 (75.0) | 3 (50.0) | 1 (25.0) | 13 (50.0) |
| Probable | 6 (50.0) | 1 (25.0) | 3 (50.0) | 3 (75.0) | 13 (50.0) |
| Primary source of infection, n )%( | |||||
| Lung | 5 (41.7) | 1 (25.0) | 3 (50.0) | 1 (25.0) | 10 (38.5) |
| Aspergillus spp | 5 | 1 | 3 | 1 | |
| Hepatosplenic | 2 (16.7) | 1 (25.0) | 1 (16.7) | 4 (15.4) | |
| C. tropicalis | 1 | 1 | |||
| C. glabrata | 1 | ||||
| Candida spp | 1 | ||||
| Paranasal sinus | 1 (8.3) | 2 (50.0) | 3 (11.5) | ||
| Aspergillus spp | 1 | ||||
| Mucormycosis | |||||
| Fungemia | 4 (33.3) | 2 (50.0) | 2 (33.3) | 1 (25.0) | 9 (34.6) |
| C. tropicalis | 1 | 2 | |||
| C. albicans | 1 | ||||
| C. krusei | 1 | ||||
| Duration of neutropenia prior to diagnosis of IFD (days) | |||||
| Median (min, max) | 12.0 (0, 23.0) | 13.0 (5, 21.0) | 16.5 (5.0, 34.0) | 73.0 (40.0, 121.0) | 16.0 (0, 121.0) |
Abbreviations: ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; IFD, invasive fungal disease; SAA, severe aplastic anemia.