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. Author manuscript; available in PMC: 2021 Jul 8.
Published in final edited form as: Adv Exp Med Biol. 2019;1184:359–372. doi: 10.1007/978-981-32-9358-8_26

Table 26.1.

Physiological and pathophysiological functions of RBPs and non-RBPs implicated in neurodegenerative diseases

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ALS: Amyotrophic Lateral Sclerosis; fALS: familial ALS; AD: Alzheimer’s disease; FXTAS: Fragile X-associated Tremor/Ataxia syndrome; FXS: fragile X syndrome; TNF-α: Tumor Necrosis Factor Alpha; NTF2-like domain: N-terminal Nuclear Transport Factor 2-like domain; FTD: Frontotemporal Dementia; SCA2: Spinocerebellar Ataxia Type 2; NPCs: Nuclear Pore Complex; NLS: Nuclear Localization Signal; mRNP: Ribonuceloprotein; RBPs: RNA binding proteins; snRNPs: Small Nuclear Ribonucleoproteins; SMA: Spinal Muscular Atrophy.