Table 1:
Baseline characteristics of cases and controls (mean ± SD, or n, %).
| Controls |
All Cases |
SQ2, SQ3 Cases |
|||||
|---|---|---|---|---|---|---|---|
| % Difference | p-value | % Difference | p-valuea | ||||
| Sample size | 266 | 135 | - | - | 52 | - | - |
| Women (n, %) | 180 (68%) | 92 (68%) | - | - | 40 (77%) | - | - |
| Age (Years) | 75.7 (5.2) | 76.3 (5.4) | 0.7 | 0.33 | 77.1 (4.9) | 0.8 | 0.49 |
| Height (cm) | 165.6 (8.1) | 165.4 (9.9) | −0.1 | 0.86 | 162.2 (7.5) | −1.5 | 0.57 |
| Weight (kg) | 74.6 (13.4) | 72.7 (14.0) | −2.5 | 0.20 | 68.2 (10.2) | −7.8 | 0.004 |
| BMI (kg/m2) | 27.1 (4.2) | 26.5 (4.3) | −2.3 | 0.17 | 25.9 (3.7) | −4.8 | 0.057 |
| Prev Fx, any (yes/no) (n, %) | 48 (18%) | 54 (40%) | 22 | <0.0001 | 18 (35%) | 15 | 0.064 |
| L Int vBMD (mg/cm3) | 175 (44) | 152 (34) | −13.3 | <0.0001 | 146 (36) | −16.6 | <0.0001 |
| L Trab vBMD (mg/cm3) | 82 (34) | 64 (28) | −22.3 | <0.0001 | 59 (26) | −25.7 | <0.0001 |
| L Strength (N) | 5,990 (2,560) | 4,710 (1,900) | −21.3 | <0.0001 | 4,240 (1670) | −26.7 | <0.0001 |
| T Int vBMD (mg/cm3) | 183 (43) | 161 (36) | −11.8 | <0.0001 | 156 (30) | −14.6 | <0.0001 |
| T Trab vBMD (mg/cm3) | 97 (36) | 80 (31) | −17.6 | <0.0001 | 78 (27) | −20.0 | 0.0002 |
| T Strength (N) | 5,130 (2,280) | 4,120 (1,760) | −19.5 | <0.0001 | 3,640 (1,200) | −27.7 | <0.0001 |
| SQ1 (n, %) | - | 83 (61%) | - | - | - | - | - |
| SQ2 (n, %) | - | 52 (39%) | - | - | 52 (100%) | - | - |
BMI = body mass index, Prev Fx = prevalent vertebral fracture, Int vBMD = integral volumetric bone mineral density, Trab vBMD = trabecular volumetric bone mineral density
a
The p-values comparing SQ2+ cases versus matched controls (n=102).